产品货号：
GS4705
中文名称：
重组大鼠IL-4
英文名称：
Recombinant Rat Interleukin-4
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
General Description
Interleukin-4 (IL-4) is a pleiotropic cytokine that induces
differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by mast cells,activated T cells and bone marrow stromal cells.It has many biological roles,including the stimulation of activated B-cell and T-cell proliferation,and the differentiation of CD4+ T-cells into Th2 cells.IL-4 can enhance both secretion and cell surface expression of IgE and IgG1 and also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.The rat IL-4 shares about 40%～45% a.a.sequence identity with human,mouse,rhesus macaque IL-4 and they are species-specific in their activities.
Storage
This lyophilized preparation is stable at 2～8℃,but should be kept at -20℃ for long term storage,preferably desiccated.
Upon reconstitution,the preparation is stable for up to one week at 2～8℃.For maximal stability,apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
Usage
This material is offered by bjbalb Biotech for research,laboratory or further evaluation purposes.
NOT FOR HUMAN USE.
Molecular Weight
Approximately 14.0kDa,a single non-glycosylatedpolypeptide chain containing 125 amino acids.
Purity
> 95% by SDS-PAGE and HPLC analyses.
Source
Escherichia coli.
Biological Activity
Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat splenocytes is less than 1.0ng/ml,corresponding to a specific activity of> 1.0×106 IU/mg.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in PBS,pH7.4,5% trehalose.
Endotoxin
Less than 1 EU/μg of rRtIL-4 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1～1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.
AA Sequence
HGCNDSPLRE IINTLNQVTE KGTPCTEMFV PDVLTATRNT
TENELICRAS RVLRKFYFPR DVPPCLKNKS GVLGELRKLC
RGVSGLNSLR SCTVNESTLT TLKDFLESLK SILRGKYLQS
CTSMS
相关搜索：重组大鼠IL-4，IL-4, Rat，Recombinant Rat Interleukin-4
Interleukin-4 (IL-4) is a pleiotropic cytokine that induces
differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by mast cells,activated T cells and bone marrow stromal cells.It has many biological roles,including the stimulation of activated B-cell and T-cell proliferation,and the differentiation of CD4+ T-cells into Th2 cells.IL-4 can enhance both secretion and cell surface expression of IgE and IgG1 and also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.The rat IL-4 shares about 40%～45% a.a.sequence identity with human,mouse,rhesus macaque IL-4 and they are species-specific in their activities.
Storage
This lyophilized preparation is stable at 2～8℃,but should be kept at -20℃ for long term storage,preferably desiccated.
Upon reconstitution,the preparation is stable for up to one week at 2～8℃.For maximal stability,apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
Usage
This material is offered by bjbalb Biotech for research,laboratory or further evaluation purposes.
NOT FOR HUMAN USE.
Molecular Weight
Approximately 14.0kDa,a single non-glycosylatedpolypeptide chain containing 125 amino acids.
Purity
> 95% by SDS-PAGE and HPLC analyses.
Source
Escherichia coli.
Biological Activity
Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using rat splenocytes is less than 1.0ng/ml,corresponding to a specific activity of> 1.0×106 IU/mg.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in PBS,pH7.4,5% trehalose.
Endotoxin
Less than 1 EU/μg of rRtIL-4 as determined by LAL method.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1～1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.
Further dilutions should be made in appropriate buffered solutions.
AA Sequence
HGCNDSPLRE IINTLNQVTE KGTPCTEMFV PDVLTATRNT
TENELICRAS RVLRKFYFPR DVPPCLKNKS GVLGELRKLC
RGVSGLNSLR SCTVNESTLT TLKDFLESLK SILRGKYLQS
CTSMS
相关搜索：重组大鼠IL-4，IL-4, Rat，Recombinant Rat Interleukin-4